Anastomotic Leak: Toward an Understanding of Its Root Causes.

Alverdy JC, Schardey HM.J Gastrointest Surg. 2021 Nov;25(11):2966-2975. doi: 10.1007/s11605-021-05048-4. Epub 2021 Jun 7.PMID: 34100248 Review.

Local antibiotic decontamination to prevent anastomotic leakage short-term outcome in rectal cancer surgery

Ulrich Wirth, Susanne Rogers, Kristina Haubensak, Stefan Schopf, Thomas von Ahnen & Hans Martin Schardey

International Journal of Colorectal Disease volume 33, pages 53–60 (2018)Cite this article

Schardey, H. M., Rogers, S., Schopf, S. K., von Ahnen, T., & Wirth, U. (2017). Are gut bacteria associated with the development of anastomotic leaks?. coloproctology, 39(2), 94-100.

Proceedings of the First International Summit on Intestinal Anastomotic Leak, Chicago, Illinois, October 4–5, 2012

Benjamin D. Shogan, Gary C. An, Hans M. Schardey, Jeffrey B. Matthews, Konstantin Umanskiy, James W. Fleshman, Jr., Jens Hoeppner, Donald E. Fry, Eduardo Garcia-Granereo, Hans Jeekel, Harry van Goor, E. Patchen Dellinger, Vani Konda, Jack A. Gilbert, Gregory W. Auner, John C. Alverdy

Surg Infect (Larchmt) 2014 Oct 1; 15(5): 479–489.  doi: 10.1089/sur.2013.114

PMCID: PMC4382716

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Prevention of anastomotic leak in rectal cancer surgery with local antibiotic decontamination: a prospective, randomized, double-blind, placebo-controlled single center trial.

Schardey HM, Wirth U, Strauss T, Kasparek MS, Schneider D, Jauch KW.Int J Colorectal Dis. 2020 May;35(5):847-857. doi: 10.1007/s00384-020-03544-8. Epub 2020 Feb 27.PMID: 32103326 Clinical Trial.

Oral antibiotic bowel decontamination in open and laparoscopic sigmoid resections for diverticular disease

Ulrich Wirth, Josefine Schardey, Thomas von Ahnen, Petra Zimmermann, Florian Kühn, Jens Werner, Hans Martin Schardey, Bettina M. Rau, Julia Gumpp

Int J Colorectal Dis. 2021; 36(8): 1667–1676.  Published online 2021 Feb 19. doi: 10.1007/s00384-021-03890-1

PMCID: PMC8279973

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Wirth U, Rogers S, Haubensak K, Schopf S, von Ahnen T, Schardey HM (2018) Local antibiotic decontamination to prevent anastomotic leakage short-term outcome in rectal cancer surgery. Int J Colorectal Dis 33(1):53–60.  https://doi.org/10.1007/s00384-017-2933-2

Schardey, H.M., Rogers, S., Schopf, S.K. et al. Sind Darmbakterien an der Entstehung der Anastomoseninsuffizienz beteiligt?. coloproctology 40, 1–8 (2018). https://doi.org/10.1007/s00053-017-0145-4

Bacteria: a major pathogenic factor for anastomotic insufficiency

HM Schardey, T Kamps, HG Rau- Antimicrobial agents …, 1994 - Am Soc Microbiol

https://doi.org/10.1128/AAC.38.11.2564

The prevention of anastomotic leakage after total gastrectomy with local decontamination. A prospective, randomized, double-blind, placebo-controlled multicenter trial.

H M Schardey, U Joosten, U Finke, K H Staubach, R Schauer, A Heiss, A Kooistra, H G Rau, R Nibler, S Lüdeling, K Unertl, G Ruckdeschel, H Exner, F W Schildberg

Ann Surg. 1997 Feb; 225(2): 172–180.  doi: 10.1097/00000658-199702000-00005

PMCID: PMC1190646

Bacteria: a major pathogenic factor for anastomotic insufficiency.

H M Schardey, T Kamps, H G Rau, S Gatermann, G Baretton, F W Schildberg

Antimicrob Agents Chemother. 1994 Nov; 38(11): 2564–2567.  doi: 10.1128/aac.38.11.2564

PMCID: PMC188242

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[Cost savings by disinfection for prevention of surgical wound dehiscence after gastrectomy].

Schardey HM, Joosten U, Finke U, Schauer R, Staubach KH, Exner H, Schildberg FW.Chirurg. 1997 Apr;68(4):416-24. doi: 10.1007/s001040050207.PMID: 9206638 Clinical Trial. German.

Schardey HM, Krämling HJ, Cramer C, et al. [Risk factors and pathogenic microorganisms in patients with insufficient esophagojejunostomy after gastrectomy]. Zentralblatt fur Chirurgie. 1998 ;123(1):46-52. PMID: 9542030.

Can oesophago-intestinal anastomotic leakage develop in the complete absence of bacteria? A comparison of normal and germ-free rats

Schardey HM, Kamps T, Rau HG, Baretton G, Gatermann S, Exner H, Schildberg FW (1997a) Can oesophago-intestinal anastomotic leakage develop in the complete absence of bacteria? A comparison of normal and germ-free rats. Int J Surg Sci 4:9–13

Schardey HM. [General infection prevention in abdominal surgery with special reference to intestinal decontamination] Zentralblatt fur Chirurgie. 1999 ;124 Suppl 4:1-8. PMID: 10670108.

Schardey H.M., Kamps T., Rau H.G., Gatermann S., Baretton G., Schildberg F.W. (1994) Bakterien — ein zentraler Faktor in der Pathogenese der Nahtinsuffizienz nach Gastrektomie in der Ratte. In: Thiede A., Lünstedt B. (eds) Standards in der Viszerosynthese. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79044-7_2

Buchbeiträge:

Schardey H.M. (2021) Pathogenese und Prävention der Nahtinsuffizienz in der onkologischen Kolonchirurgie. In: Benz S., Grützmann R., Stinner B. (eds) Chirurgie des Kolonkarzinoms. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-60453-3_26

Schardey H.M., Manert W. (2004) Prävention der Nahtinsuffzienz und andere perioperative Maßnahmen zur Prophylaxe septischer Komplikationen. In: Management des Magen- und Ösophaguskarzinoms. Onkologie aktuell. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18700-1_32